POSTER NO: 583

Phylogeography of Y chromosome lineages in the Old World

¹Vadim Stepanov, ¹Valery Puzyrev, ²Toomas Kivisild, ¹Vladimir Kharkov, ²Siiri Rootsi, ¹Maria Spiridonova, ¹Irina Khitrinskaya, ²Richard Villems
¹Institute of Medical Genetics, Nab. Ushayky 10, 634050, Tomsk, Russia, ²Estonian Biocentre, Tartu, Estonia

We have analyzed the distribution of Y chromosome haplogroups (HGs) in the Old World with the special attention to the population of North Eurasia. We have constructed the database containing data on Y chromosome lineage's frequency in 300 world populations including our experimental data on 30 populations of Siberia and Central Asia and all data published in the literature. We standardized the HGs nomenclature used by different authors to the unified format (Jobling et al. (1998), with modifications). Graphic representation of HGs distribution was made using Surfer software. The general picture of the Y lineages distribution is consistent with the hypothesis of recent African origin of modern human. Several HGs mark the following migrations of modern humans to Europe, Asia, Pacific and colonization of the New World. As to the population of North Eurasia, phylogeographic analysis reveals several components of different age and origin in their modern Y lineages pool, penetrating the territory through boreal and southern migration routs. Initial colonization of this territory, probably, through West, Middle and Central Asia in upper Paleolithic brings to the territory HG2 and 4. The next Paleolithic migration from the West is traced by HG1. After the last glacial maximum, mongoloid populations from the South, descendants of the 'austratic population' which settled South-East Asia, penetrates North Eurasia. The genetic traces of these migrants in the male gene pool are, probably, HG10 and 26. Population migrations on the territory of North Eurasia in the Neolithic form the distribution picture of HGs 3, 9, 12 and 16.